Molecular Epidemiology of Group A <em>Streptococcus</em> Infections in The Gambia
oleh: Sona Jabang, Annette Erhart, Saffiatou Darboe, Aru-Kumba Baldeh, Valerie Delforge, Gabriella Watson, Ebenezer Foster-Nyarko, Rasheed Salaudeen, Bolarinde Lawal, Grant Mackenzie, Anne Botteaux, Martin Antonio, Pierre R. Smeesters, on behalf of The MRCG StrepA Study Group
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2021-02-01 |
Deskripsi
Molecular epidemiological data on Group A <i>Streptococcus</i> (GAS) infection in Africa is scarce. We characterized the <i>emm-</i>types and <i>emm</i>-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for <i>emm</i>-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.