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In this study, natural zeolite was investigated as an inexpensive and effective adsorbent for the adsorption of malachite green (MG) from aqueous solution. The initial pH, amount of zeolite, initial dye concentration and reaction time were selected as independent variables in box behnken design while color removal efficiency was considered as the response function. The  results showed that the optimum parameter values for maximum color removal efficiency were: pH=9 , amount of zeolite 0.65 g , dye concentration 45 mg/L and reaction time 80 min . Based on analysis of variance (ANOVA), the coefficient of determination value (R2 = 0.9962) was high, showing that the experimental values fitted well with the predicted values. In addition, the statistical analysis of the results indicated that in the range studied, amount of zeolite and pH had a significant effect on color removal efficiency.