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Pheochromocytoma is a rare tumor in which seen an incidence of 1 per 100.000 in the general population. Pheochromocytoma is a catecholamine producing neuroendocrine tumor arising from adrenal medulla. A 46-year-old man experienced headache, sweating and palpitation referred to our hospital. Familial pheocromocytoma was detected. We presented this case as whole family members had suffered from morbidities and deaths due to this disorder. [Cukurova Med J 2015; 40(3.000): 593-596]