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The role of Pazopanib in Soft Tissue Sarcoma: A comprehensive review of the literature
oleh: Fotopoulos George, Pentheroudakis George
Format: | Article |
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Diterbitkan: | Sciendo 2015-09-01 |
Deskripsi
INTRODUCTION: Sarcomas are a rare and heterogeneous group of tumours of mesenchymal origin. Single agent pazopanib showed activity in a phase II clinical trial designed to screen various soft tissue sarcoma subtypes [10] and a phase III [11] clinical trial followed resulting in FDA approval in 2012 for use in metastatic soft tissue sarcoma exposed to prior chemotherapy.