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The blood parameters, total erythrocyte count (TEC), total leucocyte count (TLC), hemoglobin (Hb), blood glucose and serum protein, and size and surface area of erythrocytes of Labeo rohita exposed to two sublethal concentrations i.e 1.12 mg·l and 0.22 mg·l of quinalphos were studied. There was a decrease in the serum protein level (-20.42 to -53.03%) over control (p < 0.05) in both concentrations from at least day 15 to day 45. The blood glucose level and TLC were elevated compared to control (13.20 to 33.56% and 10.88 to 41.68%, respectively) in two sublethal concentrations from day 15 to day 45. The Hb% decreased from -23.79 to - 38.33% and TEC decreased from -2.87 to -11.32% in both sublethal concentrations.