Misalignment with the external light environment drives metabolic and cardiac dysfunction

oleh: Alexander C. West, Laura Smith, David W. Ray, Andrew S. I. Loudon, Timothy M. Brown, David A. Bechtold

Format: Article
Diterbitkan: Nature Portfolio 2017-09-01

Deskripsi

The misalignment between internal circadian rhythm and the day-night cycle can be caused by genetic, behavioural and environmental factors, and may have a profound impact on human physiology. Here West et al. show that desynchrony between the internal clock and the external environment alter metabolic parameters and cardiac function in mice.