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Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons
oleh: Ilary Allodi, Roser Montañana-Rosell, Raghavendra Selvan, Peter Löw, Ole Kiehn
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
Here the authors show in a model of ALS that motor neurons receive stronger inhibitory synaptic inputs than slow motor neurons, and disease progression is associated with specific loss of inhibitory synapses onto fast motor neurons.