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Aortic and pulmonary valves share a common developmental origin from the embryonic arterial trunk, so there are chances of involvement of both semilunar valves in the process of congenital malformation involving one valve. However, in reported literature, this is not a common association. Here, we report an infant diagnosed to have bicuspid morphology of both semilunar valves with a large perimembranous ventricular septal defect.