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<p>From June 2005 to October 2012, there were 135 cases with cerebrospinal fluid (CSF) rhinorrhea admitted in our hospital who underwent nasal endoscopic repair surgery, and intracranial infection happened in 3 cases after surgery, including intracranial mucormycosis in one case, brain abscess in one case and bacterial infection in one case. These 3 cases underwent surgery to clear up the focus of infection, supplemented by antifungal drugs or antibiotic therapy. Case 1 and Case 2 were followed up for 2 years without CSF rhinorrhea or intracranial infection; Case 3 died due to multiple organ failure. The intracranial complications after nasal endoscopic surgery for repairing CSF leakage are rare and need combined treatment of relevant departments.</p><p> </p><p>doi: 10.3969/j.issn.1672-6731.2014.08.016</p>