Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease
oleh: Jody Phelan, Paula Josefina Gomez-Gonzalez, Nuria Andreu, Yosuke Omae, Licht Toyo-Oka, Hideki Yanai, Reiko Miyahara, Supalert Nedsuwan, Paola Florez de Sessions, Susana Campino, Neneh Sallah, Julian Parkhill, Nat Smittipat, Prasit Palittapongarnpim, Taisei Mushiroda, Michiaki Kubo, Katsushi Tokunaga, Surakameth Mahasirimongkol, Martin L. Hibberd, Taane G. Clark
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
Few genetic loci have been associated with tuberculosis infection, possibly because of the influence of genetic variation in the pathogen. Here, the authors integrate human and Mycobacterium tuberculosis genetics to find genome-genome interactions associated with infection.