Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution
oleh: Xiao-Wei Hong, Yu-Qiang Zhou, Cui-Bing Bai, Nai-Xing Wang, Yalan Xing, Wei Zhang, Yan-Jing Wang, Xing-Wang Lan, Yu Xie, Yi-He Li
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2015-09-01 |
Deskripsi
An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.