Fragment synthesis of disulfide-containing peptides
oleh: Yuxuan Dai, Na Yue, Wenlong Huang, Hai Qian
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2020-01-01 |
Deskripsi
A new strategy for solid phase peptide synthesis in the fragment synthesis based on the use of 2-Cl-trityl resin as carrier to obtain protected peptide-resin and Rink Amide Resin, HOBT/HBTU or PyBOP/DIPEA or HATU/DIPEA as the coupling method is described. The highlights of this method are: • Simple. • Low cost. • Solid phase based.