Lochmolins A–G, New Sesquiterpenoids from the Soft Coral <em>Sinularia</em><em> lochmodes</em>
oleh: Jyh-Horng Sheu, Chiung-Yao Huang, Hui-Li Lin, Kuo-Ping Shen, Yen-Ju Tseng, Chang-Feng Dai
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2012-07-01 |
Deskripsi
Seven new sesquiterpenoids, lochmolins A–G (<strong>1</strong>–<strong>7</strong>), were isolated from a Taiwanese soft coral <em>Sinularia lochmodes</em>. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds <strong>1</strong>–<strong>4</strong> were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells.