Cryo-EM structure of the respiratory syncytial virus RNA polymerase
oleh: Dongdong Cao, Yunrong Gao, Claire Roesler, Samantha Rice, Paul D’Cunha, Lisa Zhuang, Julia Slack, Mason Domke, Anna Antonova, Sarah Romanelli, Shayon Keating, Gabriela Forero, Puneet Juneja, Bo Liang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-01-01 |
Deskripsi
Respiratory syncytial virus (RSV) is a pathogenic non-segmented negative-sense RNA virus and active RSV polymerase is composed of a 250 kDa large (L) protein and tetrameric phosphoprotein (P). Here, the authors present the 3.67 Å cryo-EM structure of the RSV polymerase (L:P) complex.