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Boerhaave’s syndrome (spontaneous esophageal rupture) is a rare entity, which is characterized by a rare and late diagnosis. It is a life-threatening condition and requires early diagnosis and urgent care. The most common etiological factor is emesis. A history of forceful emesis, subxiphoid chest pain, and subcutaneous emphysema is a common triad of symptoms that should suggest spontaneous rupture of the esophagus. However, sometimes confused other diseases that chest pain such as myocardial infarction, aortic aneurysm, pulmonary embolism, pneumothorax. In this report, we aim to present a patient who was diagnosed with the Boerhaave’s syndrome. In addition, we will also review the usual presenting signs, symptoms, and treatment of the Boerhaave’s syndrome.