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Structural basis for conductance through TRIC cation channels
oleh: Min Su, Feng Gao, Qi Yuan, Yang Mao, De-lin Li, Youzhong Guo, Cheng Yang, Xiao-hui Wang, Renato Bruni, Brian Kloss, Hong Zhao, Yang Zeng, Fa-ben Zhang, Andrew R Marks, Wayne A Hendrickson, Yu-hang Chen
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-05-01 |
Deskripsi
Trimeric intracellular cation channels (TRICs) elicit K+ currents to counteract luminal negative potential during Ca2+release from intracellular stores. Here the authors present structures of prokaryotic TRICs in their open and closed states, obtaining molecular insight into TRICs’ function.