PoreDesigner for tuning solute selectivity in a robust and highly permeable outer membrane pore

oleh: Ratul Chowdhury, Tingwei Ren, Manish Shankla, Karl Decker, Matthew Grisewood, Jeevan Prabhakar, Carol Baker, John H. Golbeck, Aleksei Aksimentiev, Manish Kumar, Costas D. Maranas

Format: Article
Diterbitkan: Nature Portfolio 2018-09-01

Deskripsi

Monodisperse angstrom-sized membrane proteins, found in biological membranes, are difficult to implement in synthetic industrial membranes. Here authors present a pore design procedure, to redesign the robust beta-barrel Outer Membrane Protein F (OmpF) with specific solute selectivity.