Engineering modular intracellular protein sensor-actuator devices

oleh: Velia Siciliano, Breanna DiAndreth, Blandine Monel, Jacob Beal, Jin Huh, Kiera L Clayton, Liliana Wroblewska, AnneMarie McKeon, Bruce D. Walker, Ron Weiss

Format: Article
Diterbitkan: Nature Portfolio 2018-05-01

Deskripsi

Synthetic biology principles are often used to design circuits that tune gene expression in response to changes in intracellular environments. Here the authors design a modular platform for intracellular protein sensing devices with transcriptional output.