Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria
oleh: Huan Yang, Caroline Sibilla, Raymond Liu, Jina Yun, Bruce A. Hay, Craig Blackstone, David C. Chan, Robert J. Harvey, Ming Guo
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-03-01 |
Deskripsi
Drp1 is the master regulator of mitochondrial fission, which has important impact on cellular functions. Here, Yang et al identified evolutionarily conserved proteins Clueless and its homolog CLUH as key regulators of Drp1 that function via translation of Drp1 receptors MiD49 and Mff.