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This review article reports for the first time phytochemistry, ethnobotanical uses and pharmacological activities of all <i>Cupressus</i> L. species other than <i>Cupressus sempervirens</i> L. Indeed, the literature survey showed how many other <i>Cupressus</i> species are rich of important phytochemical compounds, widely used in the ethnobotanical field for several purposes and endowed with interesting biological activities, even if they are somehow neglected by the scientific community. This review aims to continue the study of these other <i>Cupressus</i> species and promote more research on them.