Light-driven biological actuators to probe the rheology of 3D microtissues

oleh: Adrien Méry, Artur Ruppel, Jean Revilloud, Martial Balland, Giovanni Cappello, Thomas Boudou

Format: Article
Diterbitkan: Nature Portfolio 2023-02-01

Deskripsi

The mechanical properties of biological tissues are key to their integrity and function. Here, the authors engineer 3D microtissues from optogenetically modified fibroblasts and use light to quantify tissue elasticity and strain propagation using their own constituent cells as internal actuators.