Erythropoietin promotes hippocampal mitochondrial function and enhances cognition in mice
oleh: Robert A. Jacobs, Mostafa A. Aboouf, Christina Koester-Hegmann, Paola Muttathukunnel, Sofien Laouafa, Christian Arias-Reyes, Markus Thiersch, Jorge Soliz, Max Gassmann, Edith M. Schneider Gasser
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Robert Jacobs, Mostafa Aboouf, et al. examined the effect of erythropoietin (EPO) in hippocampal mitochondrial function and memory in two mouse models: one overexpressing EPO in the brain, and juvenile mice treated during three days with a high dose of intraperitoneal EPO. Their results suggest that erythropoietin in the neonatal brain may impact spatial memory by increasing mitochondrial content.