Association between Dietary Inflammatory Index and serum Klotho concentration among adults in the United States
oleh: Chichen Zhang, Zilong Zhang, Jiakun Li, Linghui Deng, Jiwen Geng, Kun Jin, Xiaonan Zheng, Shi Qiu, BiRong Dong
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2022-06-01 |
Deskripsi
Highlights 1. klotho deficiency linked to multiple premature-aging syndromes and a short lifespan 2. Proinflammatory cytokines, including TNF-α, IFN-γ, and IL-6, downregulate α-Klotho gene expression 3. Dietary Inflammatory Index was developed as a tool to determine the inflammatory potential of diet 4. We found that there was a dose–response relationship between DII and circulating concentrations of klotho in a nationally representative population of American adults.