Biomimetic nanoflowers by self-assembly of nanozymes to induce intracellular oxidative damage against hypoxic tumors
oleh: Zhenzhen Wang, Yan Zhang, Enguo Ju, Zhen Liu, Fangfang Cao, Zhaowei Chen, Jinsong Ren, Xiaogang Qu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-08-01 |
Deskripsi
Hypoxic tumors are resistant to dynamic therapy, limiting potential treatment options. Here, the authors describe a nanoflower where oxidase mimicking PtCo nanoparticles are decorated with catalase mimicking MnO2 to reverse tumor hypoxia and generate reactive oxygen species for dynamic therapy.