The lung microbiome in end-stage Lymphangioleiomyomatosis
oleh: Julie Ng, Gustavo Pacheco-Rodriguez, Lesa Begley, Yvonne J. Huang, Sergio Poli, Mark A. Perrella, Ivan O. Rosas, Joel Moss, Souheil El-Chemaly
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2021-10-01 |
Deskripsi
Abstract Lymphangioleiomyomatosis (LAM) is a progressive cystic lung disease with mortality driven primarily by respiratory failure. Patients with LAM frequently have respiratory infections, suggestive of a dysregulated microbiome. Here we demonstrate that end-stage LAM patients have a distinct microbiome signature compared to patients with end-stage chronic obstructive pulmonary disease.