The PripA-TbcrA complex-centered Rab GAP cascade facilitates macropinosome maturation in Dictyostelium
oleh: Hui Tu, Zhimeng Wang, Ye Yuan, Xilin Miao, Dong Li, Hu Guo, Yihong Yang, Huaqing Cai
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-04-01 |
Deskripsi
Macropinocytosis has emerged as an evolutionarily conserved mechanism for bulk uptake of extracellular fluid. Here they show how a Rab GAP cascade centered on the PripA-TbcrA complex facilitates Rab conversion and macropinosome maturation.