Diagnostic Potential of Differentially Expressed Homer1 and Homer2 in Ischemic Stroke
oleh: Man Zhu, Jiangcheng Zuo, Ji Shen, Wei Jing, Ping Luo, Nandi Li, Xue Wen, Chen Wang, Mingxia Yu, Chunzi Liang, Jiancheng Tu
| Format: | Article |
|---|---|
| Diterbitkan: | Cell Physiol Biochem Press GmbH & Co KG 2016-11-01 |
Deskripsi
Background: Ischemic stroke (IS) is an extremely heterogeneous disease with variable pathogenesis. Due to the lack of early diagnostic marker, the mortality rate of IS remains high worldwide. The family of Homer plays an important role in the pathology of atherosclerotic plaque. In this study, we have investigated its expression pattern and clinical significance in IS. Methods: RT-qPCR was performed to detect the expression of Homer1, Homer2, and Homer3. Results: We found that the mRNA levels of Homer1 (pConclusion: Our data suggested that Homer1 and Homer2 might be considered as novel diagnostic biomarkers for LAA stroke.