SCISSOR: a framework for identifying structural changes in RNA transcripts
oleh: Hyo Young Choi, Heejoon Jo, Xiaobei Zhao, Katherine A. Hoadley, Scott Newman, Jeremiah Holt, Michele C. Hayward, Michael I. Love, J. S. Marron, D. Neil Hayes
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Many computational tools identify mRNA variations by analyzing the transformed RNA-seq data such as collapsed reads. Here, the authors report a computational method which uses shape changes in the RNA-seq coverage profile to discover changes in mRNA expression and alternative splicing.