Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

oleh: Laila Rkieh, Wasim S. El Nekidy, Leen Oyoun Alsoud, Adnan Alatoom, Rania El Lababidi, Mohamad Mooty, Ahmad R. Nusair

Format: Article
Diterbitkan: Elsevier 2022-01-01

Deskripsi

Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including C. auris. Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.