Otilonium bromide boosts antimicrobial activities of colistin against Gram-negative pathogens and their persisters

oleh: Chen Xu, Chenyu Liu, Kaichao Chen, Ping Zeng, Edward Wai Chi Chan, Sheng Chen

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

The drug otilonium bromide restores the activity of colistin against colistinresistant Gram-negative bacteria in vitro and in a mouse infection model, suggesting that this combination may restore the value of colistin in treatment of antibiotic resistant disease.