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Otilonium bromide boosts antimicrobial activities of colistin against Gram-negative pathogens and their persisters
oleh: Chen Xu, Chenyu Liu, Kaichao Chen, Ping Zeng, Edward Wai Chi Chan, Sheng Chen
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-06-01 |
Deskripsi
The drug otilonium bromide restores the activity of colistin against colistinresistant Gram-negative bacteria in vitro and in a mouse infection model, suggesting that this combination may restore the value of colistin in treatment of antibiotic resistant disease.