High incidence of thromboembolism in patients with chronic GVHD: association with severity of GVHD and donor-recipient ABO blood group

oleh: Najla El Jurdi, Heba Elhusseini, Joan Beckman, Todd E. DeFor, Grigori Okoev, John Rogosheske, Aleksandr Lazaryan, Kristen Weiler, Veronika Bachanova, Brian C. Betts, Bruce R. Blazar, Claudio G. Brunstein, Fiona He, Shernan G. Holtan, Murali Janakiram, Radhika Gangaraju, Joseph Maakaron, Margaret L. MacMillan, Armin Rashidi, Erica D. Warlick, Smita Bhatia, Gregory Vercellotti, Daniel J. Weisdorf, Mukta Arora

Format: Article
Diterbitkan: Nature Publishing Group 2021-05-01

Deskripsi

Key points Patients with chronic GVHD after allogeneic hematopoietic cell transplantation are at high risk for thromboembolic events occurring years after diagnosis. More severe chronic GVHD, non-O donor-recipient ABO compared to O-O match and personal history of coronary artery disease are associated with higher risk of thromboembolic events.