Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores

oleh: Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro

Format: Article
Diterbitkan: Nature Portfolio 2019-10-01

Deskripsi

Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.