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Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores
oleh: Chan Cao, Nuria Cirauqui, Maria Jose Marcaida, Elena Buglakova, Alice Duperrex, Aleksandra Radenovic, Matteo Dal Peraro
Format: | Article |
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Diterbitkan: | Nature Portfolio 2019-10-01 |
Deskripsi
Aerolysin pores have potential to improve the accuracy of DNA sequencing and single-molecule proteomics. Here, the authors rationally design a set of mutated pores to achieve a more accurate detection of peptides and nucleic acids.