New Furanones from the Plant Endophytic Fungus Pestalotiopsis besseyi
oleh: Langjun Cui, Gang Ding, Yonggang Zhang, Liangdong Guo, Shuchun Liu, Haitao Liu
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2012-11-01 |
Deskripsi
Pestalafuranones A–E (compounds 1–5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A–C (compounds 1–3) displayed weak inhibitory effects against HIV-1 replication in C8166 cells, whereas pestalafuranones D (4) and E (5) showed moderate antifungal activity against the plant pathogens Verticillium dahiae and Alternaria longipes.