Crowberry inhibits cell proliferation and migration through a molecular mechanism that includes inhibition of DEK and Akt signaling in cholangiocarcinoma
oleh: Xue Wang, Xuebing Zhou, Ludan Zhang, Xin Zhang, Chunyu Yang, Yingshi Piao, Jinhua Zhao, Lili Jin, Guihua Jin, Renbo An, Xiangshan Ren
| Format: | Article |
|---|---|
| Diterbitkan: | BMC 2022-06-01 |
Deskripsi
Highlights 1. Crowberry alterd expression levels of key mediators in PI3K/Akt signaling pathway. 2. Crowberry alterd expression levels of key mediators in PI3K/Akt signaling pathway. 3. Crowberry suppressed the expression of the proto-oncogene DEK in vivo and in vitro. 4. Crowberry inhibited CCA progression and migration through a molecular mechanism that includes inhibition of DEK and the Akt signaling pathway in vivo and in vitro.