A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies
oleh: Olivia J. S. Macleod, Jean-Mathieu Bart, Paula MacGregor, Lori Peacock, Nicholas J. Savill, Svenja Hester, Sophie Ravel, Jack D. Sunter, Camilla Trevor, Steven Rust, Tristan J. Vaughan, Ralph Minter, Shabaz Mohammed, Wendy Gibson, Martin C. Taylor, Matthew K. Higgins, Mark Carrington
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-03-01 |
Deskripsi
African trypanosome infections can persist for years, but immune evasion mechanisms are not fully understood. Here, Macleod et al. identify a trypanosome receptor for mammalian factor H, a negative regulator of the alternative complement pathway, that increases parasite transmission to tsetse flies.