2-[2-(Aziridin-1-yl)ethyl]-5,5-dimethyl-2,5-dihydro-4H-benzo [e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part IV)
oleh: Helmut Spreitzer, Christiane Puschmann
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2012-10-01 |
Deskripsi
An aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.