Identification and establishment of type IV interferon and the characterization of interferon-υ including its class II cytokine receptors IFN-υR1 and IL-10R2

oleh: Shan Nan Chen, Zhen Gan, Jing Hou, Yue Cong Yang, Lin Huang, Bei Huang, Su Wang, Pin Nie

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

Interferons are critical soluble components of the inflammatory process and are composed of three types with associated receptor complexes. Here the authors identify and characterise the type IV interferon, IFN-υ, and identify its associated receptors, denote functionality during in vivo infection and ascertain its genomic localisation.