Pyrrolizidine alkaloids from Bulgarian species of the genus Senecio
oleh: NADEZHDA KOSTOVA, VESELIN CHRISTOV, MAIA CHOLAKOVA, ELENA NIKOLOVA, LIUBA EVSTATIEVA
| Format: | Article |
|---|---|
| Diterbitkan: | Serbian Chemical Society 2006-12-01 |
Deskripsi
Nine Bulgarian species from the genus Senecio were studied phytochemically and/or by GC-MS analysis. Senecivernine-N-oxide was isolated and identified by spectral data for the first time. Different types of pyrrolizidine alkaloids were tested for cytotoxicity on murine lymphocytes. At a concentration of 100 µg/ml, the alkaloid retroisosenine showed immunosuppressive effect.