In vivo three-dimensional multispectral photoacoustic imaging of dual enzyme-driven cyclic cascade reaction for tumor catalytic therapy

oleh: Shan Lei, Jing Zhang, Nicholas Thomas Blum, Meng Li, Dong-Yang Zhang, Weimin Yin, Feng Zhao, Jing Lin, Peng Huang

Format: Article
Diterbitkan: Nature Portfolio 2022-03-01

Deskripsi

Photoacoustic imaging can be used to monitor chemical reaction in cells and tissues. Here, the authors develop a Pd based nanozyme conjugated with glucose oxidase that can induce the change of photoacoustic signals during the catalytic cascade process, the system can also be used to treat tumor-bearing mice.