Cyclic microchip assay for measurement of hundreds of functional proteins in single neurons

oleh: Liwei Yang, Avery Ball, Jesse Liu, Tanya Jain, Yue-Ming Li, Firoz Akhter, Donghui Zhu, Jun Wang

Format: Article
Diterbitkan: Nature Portfolio 2022-06-01

Deskripsi

Current single-cell tools are limited by the number of proteins they can analyse. Here the authors report a single-cell cyclic multiplex in situ tagging (CycMIST) method for functional proteome profiling of single cells, allowing multiple rounds of multiplexing of the same single cells on a microchip.