Breathing-driven prefrontal oscillations regulate maintenance of conditioned-fear evoked freezing independently of initiation
oleh: Sophie Bagur, Julie M. Lefort, Marie M. Lacroix, Gaëtan de Lavilléon, Cyril Herry, Mathilde Chouvaeff, Clara Billand, Hélène Geoffroy, Karim Benchenane
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
Combining optogenetics, behavioral modelling and neural population analysis, the authors show in mice that during fear-related freezing the olfactory bulb transmits 4 Hz breathing rhythm to the prefrontal cortex where this oscillation organizes local activity and regulates freezing episode duration.