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Cluster headache (CH) is a primary headache characterized by severe pain that is strictly unilateral, with orbital, supraorbital, or temporal location, accompanied by ipsilateral autonomic manifestations. It has a considerable socioeconomic impact and impairs patients' quality of life. The present study aimed to report the case of a patient presenting with CH who underwent occipital nerve stimulation and to verify the improvement in her quality of life after this procedure.