BRCA2 Heterozygosity Delays Cytokinesis in Primary Human Fibroblasts
oleh: Asta Björk Jonsdottir, Maaike P. G. Vreeswijk, Ron Wolterbeek, Peter Devilee, Hans J. Tanke, Jorunn E. Eyfjörd, Karoly Szuhai
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2009-01-01 |
Deskripsi
Background: Inherited mutations in the tumour suppressor gene BRCA2 greatly increase the risk of developing breast, ovarian and other types of cancers. So far, most studies have focused on the role of BRCA-pathways in the maintenance of genomic stability.