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A field experiment was conducted during rainy season of 2010 at the research farm of the Indian Agricultural Research Institute, New Delhi to evaluate the performance of penoxsulam for weed management in direct-seeded and transplanted rice. The weed growth in terms of density and dry weight was relatively less in transplanted condition as compared to direct-seeded rice. Post-emergence application of penoxsulam @ 25 g/ha at 10 DAS/DAT was found more effective against weeds as compared to its application at 15 DAS/DAT. Herbicidal treatments provided a yield advantage of 66-73% over weedy check. Growth and yield attributes, grain and straw yield increased significantly with the penoxsulam at 25 g/ha applied at 10 DAS/DAT which was on par with its application at 15 DAS/DAT with the same dose. It may be concluded that weeds can be managed during critical period of competition with the application of penoxsulam at 25 g/ha at 10 DAS/DAT in both direct-seeded and transplanted rice cultures.