Structural and Pharmacological Effects of Ring-Closing Metathesis in Peptides

oleh: Pål Rongved, Øyvind Jacobsen, Jo Klaveness

Format: Article
Diterbitkan: MDPI AG 2010-09-01

Deskripsi

Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM.