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One of the impacts of climate change is the possibility of continuous increase in the incidence of vector borne disease. Dengue hemorrhagic fever (DHF) is a vector-based disease that causes many deaths in tropical countries. Previous research stated that climate variation (number of rainy days, solar radiation, humidity) was significantly related to the high incidence of dengue in Bogor city. The purpose of this research is to know the description and the correlation between climatic factors (temperature, rainfall, rainy days, solar radiation, humidity and wind speed) and the incidence of DHF in Serang District in 2007-2008. The data collected include secondary data on climatic factors and the number of dengue cases. The results of this study indicate that there was no significant correlation between the climate factors (temperature, rainfall, rainy days, solar radiation, humidity, and wind speed) and the incidence rate of DHF in Serang District in 2007-2008. The reasons for this are the following: the data were not collected for a sufficiently long period of time; the obtained climate data were incomplete; and there was insufficient data on the frequency of DHF incidences taken.