Neisseria meningitidis Serogroup X in Sub-Saharan Africa

oleh: Alain Agnememel, Eva Hong, Dario Giorgini, Viginia Nuñez-Samudio, Ala-Eddine Deghmane, Muhamed-Kheir Taha

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2016-04-01

Deskripsi

The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.