Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization
oleh: Marjolein B. M. Meddens, Elvis Pandzic, Johan A. Slotman, Dominique Guillet, Ben Joosten, Svenja Mennens, Laurent M. Paardekooper, Adriaan B. Houtsmuller, Koen van den Dries, Paul W. Wiseman, Alessandra Cambi
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-10-01 |
Deskripsi
Podosomes are adhesive cytoskeletal structures found in several cell types, but whether or how they are interconnected is not known. Here the authors demonstrate mesoscale connectivity of podosome clusters by imaging directional flow patterns of podosome components vinculin, talin and F-actin.