High-spatial and colourimetric imaging of histone modifications in single senescent cells using plasmonic nanoprobes

oleh: Hyun Ji An, Yun Kim, Soojeong Chang, Hakchun Kim, Jihwan Song, Hyunsung Park, Inhee Choi

Format: Article
Diterbitkan: Nature Portfolio 2021-10-01

Deskripsi

The authors demonstrate a colourimetric imaging method using plasmonic nanoparticles for visualisation of heterochromatin histone markers. Based on the distance-dependent coupling effect, resulting in spectral shifts, they observe reorganisation of histone markers caused by oncogene-induced senescence.