Generation of iPSC line epiHUVEC from human umbilical vein endothelial cells

oleh: Peggy Matz, James Adjaye

Format: Article
Diterbitkan: Elsevier 2015-11-01

Deskripsi

Human umbilical vein endothelial cells (HUVECs) were used to generate the iPSC line epiHUVEC employing a combination of three episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC and KLF4. Pluripotency was confirmed both in vivo and in vitro. The transcriptome profile of epiHUVEC and the human embryonic stem cell line — H1 have a Pearson correlation of 0.899.