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Generation of iPSC line epiHUVEC from human umbilical vein endothelial cells
oleh: Peggy Matz, James Adjaye
Format: | Article |
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Diterbitkan: | Elsevier 2015-11-01 |
Deskripsi
Human umbilical vein endothelial cells (HUVECs) were used to generate the iPSC line epiHUVEC employing a combination of three episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC and KLF4. Pluripotency was confirmed both in vivo and in vitro. The transcriptome profile of epiHUVEC and the human embryonic stem cell line — H1 have a Pearson correlation of 0.899.